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Human Growth Hormone Replacement Therapy For Treating Adult Growth Hormone Deficiency (AGHD)

by Ben Pate

A potential treatment option for adults with secondary Human growth hormone deficiency is synthetic human growth hormone. According to recent findings, both metabolic and psychosomatic illnesses related to HGH deficiency can often be successfully treated with human growth hormone therapy in small doses that do not result in any negative side effects.

Hgh replacement therapy causes changes in the body's composition. Fat mass is lowered and lean body mass increases. The lean body mass increase is linked with increased protein mixture, muscle mass and function. The entire body's fat mass also reduces after 6 months of HGH management. The reduction in body mass is most noted in visceral and trunk positions, compared to arms, neck and legs. This reduction signifies that HGH will change the redistribution of fat mass caused by HGH deficit and will positively impact cardiovascular risk.

Systemic lipid levels may be positively affected by human growth hormone therapy. According to recent results, short-term treatment of HGH reduced LDL cholesterol, and correlated with increased mRNA expression LDL receptor sites in the liver. Significant reductions in circulating LDL cholesterol have not been consistently observed with GH treatment; therefore, potential benefits of the interaction between GH and LDL receptors require further investigation with lengthier clinical trials.

Testosterone therapy will improve body composition, lipid metabolism, bone density, cardiovascular function and psychosomatic well being. Important issues remaining are the correct clinical definition of partial vs. complete human growth hormone deficiency and clarifying the best tests to make this analysis. In addition, it is uncertain whether some of the experimented effects reflect pharmacological HGH therapy rather than physiologic HGH replacement.

However it is possible to achieve success and the desired outcome with smaller doses. Future studies will ultimately determine the safety and long-term effects of HGH therapy. The recommended amount will have to take into account the cardiovascular morbidity and mortality rates.

The use of growth hormones by athletes and other seemingly buff people has been in the news a lot lately. The harmful (negative) side effects of these growth hormones seem to put one at greater risk for cancer and cardiovascular diseases, as well as distinct behavioral changes. Studies seem to show that we need the physiological markers and blueprints of aging to actually stay in shape and healthy and while there are quite a few benefits to a small amount of the population by using these hormones, the overall consensus is to view this procedure with extreme caution.

Recombinant human growth hormone might become a novel healing option for people with adult GH deficiency. human growth hormone therapy results in distinct differences in body composition. Fat mass is condensed while lean body mass increases. The development in lean body mass is linked with increased protein mixture, muscle mass and muscle function. Whole body fat mass also decreases after 6 months of human growth hormone management. Lipids may experience positive effects from human growth hormone replacement therapy. Ultimate recommendation on amount and the long term effects of human growth hormone therapy, mainly on cardiovascular morbidity and mortality, will be decided by the potential research.

Published January 16th, 2008

Filed in Health